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IGF-DES

LIMITED EVIDENCE

Also known as: IGF-1 DES(1-3)

Investigational — not approved for human use

Educational Overview
A truncated IGF-1 variant lacking the first three amino acids, giving markedly reduced binding-protein affinity.
Research Mechanism
Reduced IGFBP binding results in higher free-fraction activity in study models compared with intact IGF-1.
Areas of Study
  • Cell culture research
  • Growth-factor signalling (in vitro)
Safety Considerations
Human safety is not established. Growth-factor signalling carries theoretical proliferative risk. Prohibited in sport. Research material only.
Frequently Asked Questions
Is this approved for human use?
No. This material is supplied for laboratory research use only by qualified businesses and institutions. It is not a medicine and is not for human or veterinary consumption.
How do I get pricing?
Request a quote and our team will respond with current pricing and available sizes for your account.
Do you provide purity documentation?
Certificates of analysis are available to approved accounts. Contact our team for batch-specific documentation.
References
References pending editorial review

We publish citations only after a qualified reviewer has verified them against the primary literature. We do not list references we have not checked. (1 queued.)

Last reviewed: 2026-07-23 · Status: in_review · References verified by editorial review before publication.

Disclaimer: Educational only. Not medical advice, diagnosis, or treatment. For research and educational purposes. Consult a licensed medical professional.