VANGUARDPERFORMANCE LABS
Peptide Education

What the Science Actually Says

Evidence-based information to help you make informed decisions. Every entry is graded honestly — including where the research is thin.

61 of 61 compounds

5-Amino-1MQ

MetabolicLIMITED EVIDENCE

5-amino-1-methylquinolinium

A small-molecule NNMT inhibitor studied in preclinical metabolic models. Not a peptide despite frequently appearing in peptide catalogs.

Research Focus
NNMT inhibition (preclinical)
Status
Investigational — not approved for human use

ACE-031

Growth FactorMODERATE EVIDENCE

ActRIIB-Fc · Activin receptor fusion protein

A soluble activin receptor fusion protein studied as a myostatin pathway inhibitor. Clinical development was discontinued after adverse findings in trials.

Research Focus
Myostatin pathway research
Status
Investigational — clinical development discontinued

Adipotide

MetabolicLIMITED EVIDENCE

FTPP · Prohibitin-targeting peptide

A peptidomimetic studied in preclinical models for targeted effects on adipose tissue vasculature.

Research Focus
Adipose vasculature (preclinical)
Status
Investigational — not approved for human use

AHK-Cu

Skin / HairLIMITED EVIDENCE

Alanine-Histidine-Lysine copper

A copper-binding tripeptide related to GHK-Cu, studied primarily in topical and cosmetic research contexts for hair and scalp applications.

Research Focus
Topical hair/scalp research
Status
Cosmetic and research use

AICAR

MetabolicMODERATE EVIDENCE

Acadesine · AICA ribonucleotide

A nucleoside analogue widely used as a laboratory tool compound to study AMP-activated protein kinase signalling.

Research Focus
AMPK signalling (in vitro and preclinical)
Status
Investigational — not approved for human use

AOD-9604

MetabolicLIMITED EVIDENCE

Anti-Obesity Drug 9604 · hGH fragment 176-191

A modified fragment of the human growth hormone molecule, studied in preclinical models for effects on fat metabolism without the full growth-signalling profile of intact hGH.

Research Focus
Adipose metabolism (preclinical)
Status
Investigational — not approved for human use

ARA-290

NeuroMODERATE EVIDENCE

Cibinetide · Helix B surface peptide

An 11-amino-acid peptide derived from erythropoietin's helix B, engineered to retain tissue-protective signalling without erythropoietic activity.

Research Focus
Small-fibre neuropathy (clinical trials)
Status
Investigational — completed clinical trials, not approved

BAM15

MetabolicLIMITED EVIDENCE

A mitochondrial uncoupling agent studied in preclinical metabolic research as a more selective alternative to older uncouplers.

Research Focus
Mitochondrial uncoupling (preclinical)
Status
Investigational — not approved for human use

BPC-157

RecoveryLIMITED EVIDENCE

Body Protection Compound 157

A synthetic peptide derived from a sequence identified in gastric juice, studied in preclinical models for tissue and tendon repair.

Research Focus
Tendon/ligament healing (animal)
Status
Investigational — not approved for human use

BPC-157 + TB-500

RecoveryLIMITED EVIDENCE

Blend · BPC157/TB500

A combination preparation containing two peptides studied separately in preclinical tissue-repair models. Blends are supplied for research convenience; combination effects have not been characterised in controlled human trials.

Research Focus
Combination tissue-repair models (preclinical)
Status
Investigational blend — not approved for human use

Cagrilintide

MetabolicMODERATE EVIDENCE

AM833

A long-acting amylin analogue under clinical investigation for metabolic and appetite-regulation research, studied both alone and alongside GLP-1 receptor agonists.

Research Focus
Appetite regulation (clinical trials)
Status
Investigational — in clinical trials, not approved

CagriSema

MetabolicMODERATE EVIDENCE

Cagrilintide + Semaglutide

A combination preparation of an amylin analogue with a GLP-1 receptor agonist, under clinical investigation for metabolic research.

Research Focus
Combination metabolic trials
Status
Investigational combination — not approved; contains an analogue of an approved drug class

CJC-1295

GrowthLIMITED EVIDENCE

GHRH analogue

A growth-hormone-releasing hormone analogue studied for its effect on GH and IGF-1.

Research Focus
GH/IGF-1 response (small human studies)
Status
Investigational

CJC-1295 no DAC + Ipamorelin

Growth Hormone SecretagogueLIMITED EVIDENCE

Blend

A combination preparation of a GHRH analogue and a ghrelin-receptor agonist, supplied together for research convenience.

Research Focus
Combination GH-axis research (preclinical)
Status
Investigational blend — not approved for human use

CJC-1295 with DAC

Growth Hormone SecretagogueLIMITED EVIDENCE

CJC-1295 DAC · Drug Affinity Complex GHRH analogue

A GHRH analogue incorporating a drug affinity complex that substantially extends its half-life compared with the non-DAC form.

Research Focus
GH-axis signalling (preclinical)
Status
Investigational — not approved for human use

Dihexa

NeuroINSUFFICIENT EVIDENCE

N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

A small-molecule angiotensin IV analogue studied in preclinical models for effects on synaptic connectivity.

Research Focus
Synaptogenesis (preclinical)
Status
Investigational — not approved for human use

DSIP

NeuroINSUFFICIENT EVIDENCE

Delta Sleep-Inducing Peptide

A nonapeptide first isolated in the 1970s from cerebral venous blood in animal studies, investigated for possible relationships to sleep-phase regulation.

Research Focus
Sleep-phase research (preclinical, historical)
Status
Investigational — not approved for human use

Epithalon

LongevityINSUFFICIENT EVIDENCE

Epitalon · AEDG peptide

A synthetic tetrapeptide studied primarily in Russian-language literature for reported effects on telomerase activity and pineal function in animal models.

Research Focus
Telomere biology (preclinical)
Status
Investigational — not approved for human use

Follistatin

Growth FactorMODERATE EVIDENCE

FST

A glycoprotein that binds and neutralises members of the TGF-beta family including myostatin, studied in muscle and reproductive biology.

Research Focus
Muscle biology research
Status
Research protein — not for human use

FOXO4

LongevityLIMITED EVIDENCE

FOXO4-DRI · Senolytic peptide

A retro-inverso peptide studied in preclinical senescence research as a senolytic tool compound.

Research Focus
Cellular senescence (preclinical)
Status
Investigational — not approved for human use

GDF-8

Growth FactorSTRONG EVIDENCE

Myostatin · Growth Differentiation Factor 8

The myostatin protein itself, a well-characterised negative regulator of muscle mass, supplied as a research protein for laboratory study.

Research Focus
Muscle biology research
Status
Research protein — not for human use

GHK-Cu

Skin / HairMODERATE EVIDENCE

Copper peptide

A copper-binding tripeptide studied primarily in topical/cosmetic contexts for skin.

Research Focus
Topical skin studies (human)
Status
Cosmetic and research use

GHRP-2

Growth Hormone SecretagogueMODERATE EVIDENCE

Pralmorelin

A growth-hormone-releasing peptide studied for its GH secretagogue activity; used diagnostically in some jurisdictions.

Research Focus
GH-axis research
Status
Investigational in most territories — not FDA approved

GHRP-6

Growth Hormone SecretagogueMODERATE EVIDENCE

One of the earliest studied growth-hormone-releasing peptides, notable in research for pronounced appetite-stimulating effects alongside GH release.

Research Focus
GH-axis research
Status
Investigational — not approved for human use

Glow Blend

RecoveryLIMITED EVIDENCE

Blend

A multi-peptide research preparation combining compounds studied individually in tissue and dermal research models.

Research Focus
Dermal and tissue research (preclinical)
Status
Investigational blend — not approved for human use

GLP2-Tirz

MetabolicSTRONG EVIDENCE

Tirzepatide analogue

A dual GIP/GLP-1 receptor agonist analogue. The reference molecule has been extensively studied in large controlled trials and is the active ingredient of FDA-approved prescription products.

Research Focus
Glycaemic control (clinical)
Status
Analogue of an approved drug substance — research supply is NOT an approved medicine

Hexarelin

Growth Hormone SecretagogueMODERATE EVIDENCE

Examorelin

A synthetic hexapeptide GH secretagogue studied for both pituitary and cardiac-tissue effects in research models.

Research Focus
GH-axis research
Status
Investigational — not approved for human use

HGH Fragment 176-191

MetabolicLIMITED EVIDENCE

AOD-related fragment · Lipolytic fragment

A C-terminal fragment of the growth hormone molecule studied in preclinical models for effects on fat metabolism without the growth-signalling activity of intact hGH.

Research Focus
Adipose metabolism (preclinical)
Status
Investigational — not approved for human use

IGF-1 LR3

Growth FactorLIMITED EVIDENCE

Long R3 IGF-1

A modified insulin-like growth factor analogue with reduced binding-protein affinity, used widely as a cell-culture supplement in laboratory research.

Research Focus
Cell culture research
Status
Investigational — not approved for human use

IGF-DES

Growth FactorLIMITED EVIDENCE

IGF-1 DES(1-3)

A truncated IGF-1 variant lacking the first three amino acids, giving markedly reduced binding-protein affinity.

Research Focus
Cell culture research
Status
Investigational — not approved for human use

Ipamorelin

GrowthMODERATE EVIDENCE

GH secretagogue

A growth-hormone secretagogue studied for its selective GH-releasing effect.

Research Focus
GH response (human studies)
Status
Investigational

KissPeptin-10

NeuroMODERATE EVIDENCE

Metastin fragment · KP-10

A fragment of the kisspeptin protein studied for its central role in reproductive-axis signalling, including in published human research settings.

Research Focus
Reproductive-axis signalling (clinical research)
Status
Investigational — not approved for human use

KLOW Blend

RecoveryLIMITED EVIDENCE

GHK-Cu + TB-500 + BPC-157 + KPV

A four-component research preparation combining copper peptide, thymosin fragment, gastric pentadecapeptide, and a tripeptide studied in inflammation models.

Research Focus
Combination tissue-repair research (preclinical)
Status
Investigational blend — not approved for human use

KPV

Immune / SkinLIMITED EVIDENCE

Lys-Pro-Val · alpha-MSH fragment

A short tripeptide fragment of alpha-MSH studied in preclinical models for inflammatory signalling.

Research Focus
Inflammatory models (animal)
Status
Investigational — not approved for human use

LL-37

ImmuneMODERATE EVIDENCE

Cathelicidin · hCAP-18 fragment

The only known human cathelicidin antimicrobial peptide, studied extensively in innate immunity and wound research.

Research Focus
Antimicrobial research
Status
Investigational — not approved for human use

Mazdutide

MetabolicMODERATE EVIDENCE

IBI362 · LY3305677

A GLP-1 and glucagon receptor dual agonist based on oxyntomodulin, under clinical investigation primarily in Asian markets.

Research Focus
Metabolic regulation (clinical trials)
Status
Investigational — in clinical trials, not approved

Melatonin

LongevitySTRONG EVIDENCE

N-acetyl-5-methoxytryptamine

A well-characterised hormone central to circadian regulation. Oral forms are widely available as regulated dietary supplements; this is supplied as research material.

Research Focus
Circadian biology
Status
Research material — oral supplements are separately regulated

MGF

Growth FactorLIMITED EVIDENCE

Mechano Growth Factor · IGF-1Ec splice variant

A splice variant of IGF-1 expressed in response to mechanical loading, studied in muscle-repair research models.

Research Focus
Muscle repair (preclinical)
Status
Investigational — not approved for human use

MOTS-c

MetabolicLIMITED EVIDENCE

Mitochondrial ORF of the 12S rRNA type-c

A mitochondria-derived peptide studied for roles in metabolic regulation and exercise physiology.

Research Focus
Metabolic models (animal)
Status
Investigational — not approved for human use

MT-1

OtherMODERATE EVIDENCE

Melanotan 1 · Afamelanotide analogue

An alpha-MSH analogue studied for effects on melanogenesis. A related molecule holds narrow regulatory approval in some jurisdictions for a rare photosensitivity condition.

Research Focus
Melanogenesis research
Status
Analogue of a compound approved in limited territories — research supply is not a medicine

MT-2

OtherLIMITED EVIDENCE

Melanotan 2

A non-selective melanocortin receptor agonist studied for pigmentation effects. Never approved by any regulator.

Research Focus
Melanogenesis research (preclinical)
Status
Investigational — not approved for human use

NAD+

LongevityMODERATE EVIDENCE

Nicotinamide adenine dinucleotide

A coenzyme central to cellular energy metabolism. Precursors are widely studied; direct NAD+ administration is less well characterised.

Research Focus
Precursor supplementation (human trials)
Status
Sold as a supplement/research material; IV and injectable use is not FDA-approved

PE-22-28

NeuroINSUFFICIENT EVIDENCE

Spadin analogue

A spadin-derived peptide studied in animal models for effects on TREK-1 channel activity.

Research Focus
TREK-1 channel research (preclinical)
Status
Investigational — not approved for human use

PEG-MGF

Growth FactorLIMITED EVIDENCE

PEGylated Mechano Growth Factor

A PEGylated form of mechano growth factor with extended stability compared with the unmodified peptide.

Research Focus
Muscle repair (preclinical)
Status
Investigational — not approved for human use

Pinealon

LongevityINSUFFICIENT EVIDENCE

EDR peptide

A synthetic tripeptide studied primarily in Russian-language literature for reported neuroprotective effects in animal models.

Research Focus
Neuroprotection models (preclinical)
Status
Investigational — not approved for human use

PNC-27

OtherLIMITED EVIDENCE

p53-derived peptide

A peptide derived from a p53 domain fused to a membrane-penetrating sequence, studied in cancer cell-line research.

Research Focus
Cancer cell-line research (in vitro)
Status
Investigational — not approved for human use

PT-141

NeuroMODERATE EVIDENCE

Bremelanotide

A melanocortin receptor agonist. The reference molecule completed clinical trials and is the active ingredient of an FDA-approved prescription product for a specific indication.

Research Focus
Melanocortin signalling (clinical)
Status
Analogue of an approved drug substance — research supply is NOT an approved medicine

Reconstitution Solution

Laboratory SupplySTRONG EVIDENCE

Bacteriostatic diluent

A sterile diluent used in laboratory settings to reconstitute lyophilised research materials for in-vitro work and analysis.

Research Focus
Laboratory sample preparation
Status
Laboratory supply — not a therapeutic product

RT

MetabolicMODERATE EVIDENCE

Retatrutide · GLP3-Reta · Triple agonist (GLP-1/GIP/glucagon)

An investigational triple-agonist studied in large trials for weight and metabolic outcomes. Not FDA-approved and has no legal compounding pathway.

Research Focus
Weight reduction (Phase 3 human trials)
Status
Investigational — Phase 3 (not approved; anticipated ~2027)

Selank

NeuroINSUFFICIENT EVIDENCE

TP-7

A synthetic heptapeptide derived from tuftsin, studied primarily in Russian research literature for effects on anxiety-related behaviour in animal models.

Research Focus
Anxiolytic behaviour models (preclinical)
Status
Investigational — not approved for human use

Semax

NeuroINSUFFICIENT EVIDENCE

ACTH(4-10) analogue

A synthetic peptide derived from a fragment of adrenocorticotropic hormone, studied largely in Russian literature for neuroprotective and cognitive endpoints in animal models.

Research Focus
Neuroprotection models (preclinical)
Status
Investigational — not approved for human use

Sermorelin

Growth Hormone SecretagogueMODERATE EVIDENCE

GRF 1-29

A growth-hormone-releasing hormone analogue comprising the first 29 amino acids of GHRH. Historically used diagnostically before withdrawal from the US market for commercial reasons.

Research Focus
GH-axis diagnostics (historical clinical)
Status
Previously approved for a specific indication; research supply is NOT an approved medicine

SLU-PP-332

MetabolicLIMITED EVIDENCE

A small-molecule ERR agonist studied in preclinical models as an exercise-mimetic tool compound.

Research Focus
Exercise-mimetic research (preclinical)
Status
Investigational — not approved for human use

SNAP-8

Skin / HairMODERATE EVIDENCE

Acetyl Octapeptide-3

An eight-amino-acid peptide used widely as a topical cosmetic ingredient, studied for effects on expression-line appearance.

Research Focus
Topical cosmetic studies
Status
Cosmetic ingredient

SS-31

MitochondrialMODERATE EVIDENCE

Elamipretide

A mitochondria-targeting peptide that has been evaluated in human clinical trials for mitochondrial disease indications.

Research Focus
Primary mitochondrial myopathy (human trials)
Status
Investigational — studied in clinical trials, not approved

Survodutide

MetabolicMODERATE EVIDENCE

BI 456906

A dual GLP-1 and glucagon receptor agonist under clinical investigation for metabolic research. Not approved by any regulator.

Research Focus
Metabolic regulation (clinical trials)
Status
Investigational — in clinical trials, not approved

TB-500

RecoveryLIMITED EVIDENCE

Thymosin beta-4 fragment

A synthetic fragment related to thymosin beta-4, studied in animal and laboratory models for tissue repair.

Research Focus
Wound/tissue models (animal)
Status
Investigational — not approved for human use

Tesamorelin

Growth Hormone SecretagogueSTRONG EVIDENCE

TH9507

A stabilised GHRH analogue. The reference molecule completed controlled clinical trials and is the active ingredient of an FDA-approved prescription product for a specific, narrow indication.

Research Focus
Visceral adiposity (clinical trials)
Status
Analogue of an approved drug substance — research supply is NOT an approved medicine

Thymalin

ImmuneINSUFFICIENT EVIDENCE

Thymus peptide complex

A thymus-derived peptide preparation studied largely in Russian-language literature for immunomodulatory endpoints.

Research Focus
Immune modulation (preclinical)
Status
Investigational — not approved for human use

Thymosin Alpha-1

ImmuneMODERATE EVIDENCE

Ta1 · Thymalfasin

A 28-amino-acid peptide derived from prothymosin alpha, studied for immunomodulatory activity. Approved for certain indications in some jurisdictions but not by the FDA.

Research Focus
Immune modulation (clinical, non-US)
Status
Approved in some countries; NOT approved in the US — research supply is not a medicine

VIP Peptide

ImmuneMODERATE EVIDENCE

Vasoactive Intestinal Peptide · Aviptadil analogue

A 28-amino-acid neuropeptide with broad signalling roles, studied in pulmonary and immune research contexts.

Research Focus
Pulmonary research (clinical trials)
Status
Investigational — not approved for general use
Disclaimer: Educational only. Not medical advice, diagnosis, or treatment. For research and educational purposes. Consult a licensed medical professional.