VANGUARDPERFORMANCE LABS
Scientific Research

How We Read the Evidence

Most peptide marketing treats every compound as equally proven. It isn't. We publish an explicit evidence grade with every entry so you can tell the difference between a well-studied therapeutic and an interesting animal result.

Our evidence grades

STRONG EVIDENCE

Multiple well-designed human trials with consistent findings. Regulatory review or approval in at least one indication.

MODERATE EVIDENCE

Human studies exist but are limited in size, duration, or consistency. Direction is promising; certainty is not.

LIMITED EVIDENCE

Mostly animal or in-vitro work. Little or no controlled human data. Popular online ≠ proven.

INSUFFICIENT EVIDENCE

Not enough credible published work to characterize at all.

Where each compound currently sits

Grades are reviewed as new research publishes. Last review date appears on every profile.

CompoundCategoryEvidenceStatus
BPC-157RecoveryLIMITED EVIDENCEInvestigational — not approved for human use
TB-500RecoveryLIMITED EVIDENCEInvestigational — not approved for human use
GHK-CuSkin / HairMODERATE EVIDENCECosmetic and research use
CJC-1295GrowthLIMITED EVIDENCEInvestigational
IpamorelinGrowthMODERATE EVIDENCEInvestigational
RTMetabolicMODERATE EVIDENCEInvestigational — Phase 3 (not approved; anticipated ~2027)
KPVImmune / SkinLIMITED EVIDENCEInvestigational — not approved for human use
MOTS-cMetabolicLIMITED EVIDENCEInvestigational — not approved for human use
SS-31MitochondrialMODERATE EVIDENCEInvestigational — studied in clinical trials, not approved
NAD+LongevityMODERATE EVIDENCESold as a supplement/research material; IV and injectable use is not FDA-approved
AOD-9604MetabolicLIMITED EVIDENCEInvestigational — not approved for human use
BPC-157 + TB-500RecoveryLIMITED EVIDENCEInvestigational blend — not approved for human use
CagrilintideMetabolicMODERATE EVIDENCEInvestigational — in clinical trials, not approved
CagriSemaMetabolicMODERATE EVIDENCEInvestigational combination — not approved; contains an analogue of an approved drug class
CJC-1295 no DAC + IpamorelinGrowth Hormone SecretagogueLIMITED EVIDENCEInvestigational blend — not approved for human use
DSIPNeuroINSUFFICIENT EVIDENCEInvestigational — not approved for human use
EpithalonLongevityINSUFFICIENT EVIDENCEInvestigational — not approved for human use
Glow BlendRecoveryLIMITED EVIDENCEInvestigational blend — not approved for human use
GLP2-TirzMetabolicSTRONG EVIDENCEAnalogue of an approved drug substance — research supply is NOT an approved medicine
IGF-1 LR3Growth FactorLIMITED EVIDENCEInvestigational — not approved for human use
PT-141NeuroMODERATE EVIDENCEAnalogue of an approved drug substance — research supply is NOT an approved medicine
Reconstitution SolutionLaboratory SupplySTRONG EVIDENCELaboratory supply — not a therapeutic product
SelankNeuroINSUFFICIENT EVIDENCEInvestigational — not approved for human use
SemaxNeuroINSUFFICIENT EVIDENCEInvestigational — not approved for human use
SermorelinGrowth Hormone SecretagogueMODERATE EVIDENCEPreviously approved for a specific indication; research supply is NOT an approved medicine
TesamorelinGrowth Hormone SecretagogueSTRONG EVIDENCEAnalogue of an approved drug substance — research supply is NOT an approved medicine
Thymosin Alpha-1ImmuneMODERATE EVIDENCEApproved in some countries; NOT approved in the US — research supply is not a medicine
AHK-CuSkin / HairLIMITED EVIDENCECosmetic and research use
KLOW BlendRecoveryLIMITED EVIDENCEInvestigational blend — not approved for human use
CJC-1295 with DACGrowth Hormone SecretagogueLIMITED EVIDENCEInvestigational — not approved for human use
SNAP-8Skin / HairMODERATE EVIDENCECosmetic ingredient
PinealonLongevityINSUFFICIENT EVIDENCEInvestigational — not approved for human use
MT-1OtherMODERATE EVIDENCEAnalogue of a compound approved in limited territories — research supply is not a medicine
MT-2OtherLIMITED EVIDENCEInvestigational — not approved for human use
ACE-031Growth FactorMODERATE EVIDENCEInvestigational — clinical development discontinued
AICARMetabolicMODERATE EVIDENCEInvestigational — not approved for human use
AdipotideMetabolicLIMITED EVIDENCEInvestigational — not approved for human use
GHRP-2Growth Hormone SecretagogueMODERATE EVIDENCEInvestigational in most territories — not FDA approved
GHRP-6Growth Hormone SecretagogueMODERATE EVIDENCEInvestigational — not approved for human use
HexarelinGrowth Hormone SecretagogueMODERATE EVIDENCEInvestigational — not approved for human use
MGFGrowth FactorLIMITED EVIDENCEInvestigational — not approved for human use
PEG-MGFGrowth FactorLIMITED EVIDENCEInvestigational — not approved for human use
KissPeptin-10NeuroMODERATE EVIDENCEInvestigational — not approved for human use
ThymalinImmuneINSUFFICIENT EVIDENCEInvestigational — not approved for human use
ARA-290NeuroMODERATE EVIDENCEInvestigational — completed clinical trials, not approved
VIP PeptideImmuneMODERATE EVIDENCEInvestigational — not approved for general use
DihexaNeuroINSUFFICIENT EVIDENCEInvestigational — not approved for human use
HGH Fragment 176-191MetabolicLIMITED EVIDENCEInvestigational — not approved for human use
LL-37ImmuneMODERATE EVIDENCEInvestigational — not approved for human use
5-Amino-1MQMetabolicLIMITED EVIDENCEInvestigational — not approved for human use
PE-22-28NeuroINSUFFICIENT EVIDENCEInvestigational — not approved for human use
BAM15MetabolicLIMITED EVIDENCEInvestigational — not approved for human use
PNC-27OtherLIMITED EVIDENCEInvestigational — not approved for human use
FOXO4LongevityLIMITED EVIDENCEInvestigational — not approved for human use
SLU-PP-332MetabolicLIMITED EVIDENCEInvestigational — not approved for human use
GDF-8Growth FactorSTRONG EVIDENCEResearch protein — not for human use
FollistatinGrowth FactorMODERATE EVIDENCEResearch protein — not for human use
IGF-DESGrowth FactorLIMITED EVIDENCEInvestigational — not approved for human use
SurvodutideMetabolicMODERATE EVIDENCEInvestigational — in clinical trials, not approved
MazdutideMetabolicMODERATE EVIDENCEInvestigational — in clinical trials, not approved
MelatoninLongevitySTRONG EVIDENCEResearch material — oral supplements are separately regulated

How to read a study

Animal ≠ human

A result in rodents is a hypothesis about humans, not a finding in them. Most peptide research stops here.

Size and duration

A 12-person, 4-week study can show a signal. It cannot establish safety over years.

Who funded it

Funding doesn't invalidate research, but it belongs in how you weigh a single positive result.

Disclaimer: Educational only. Not medical advice, diagnosis, or treatment. For research and educational purposes. Consult a licensed medical professional.