VANGUARDPERFORMANCE LABS
← Education Library

SS-31

MODERATE EVIDENCE

Also known as: Elamipretide

Investigational — studied in clinical trials, not approved

Educational Overview
A mitochondria-targeting peptide that has been evaluated in human clinical trials for mitochondrial disease indications.
Research Mechanism
Associates with cardiolipin in the inner mitochondrial membrane; studied for effects on mitochondrial function.
Areas of Study
  • Primary mitochondrial myopathy (human trials)
  • Cardiac and renal models
Safety Considerations
Has undergone clinical study, but is not approved. Trial outcomes have been mixed.
Frequently Asked Questions
Has SS-31 been in human trials?
Yes — elamipretide has been studied in clinical trials, with mixed results and no approval.
References
References pending editorial review

We publish citations only after a qualified reviewer has verified them against the primary literature. We do not list references we have not checked. (1 queued.)

Last reviewed: 2026-06-01 · Status: draft · References verified by editorial review before publication.

Disclaimer: Educational only. Not medical advice, diagnosis, or treatment. For research and educational purposes. Consult a licensed medical professional.